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ProNGF Drives Localized and Cell Selective Parvalbumin Interneuron and Perineuronal Net Depletion in the Dentate Gyrus of Transgenic Mice
ProNGF, the precursor of mature Nerve Growth Factor (NGF), is the most abundant NGF form in the brain and increases markedly in the cortex in Alzheimer's Disease (AD), relative to mature NGF. A large body of evidence shows that the actions of ProNGF and mature NGF are often conflicting, dependi...
Autores principales: | Fasulo, Luisa, Brandi, Rossella, Arisi, Ivan, La Regina, Federico, Berretta, Nicola, Capsoni, Simona, D'Onofrio, Mara, Cattaneo, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299926/ https://www.ncbi.nlm.nih.gov/pubmed/28232789 http://dx.doi.org/10.3389/fnmol.2017.00020 |
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