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Why calpain inhibitors are interesting leading compounds to search for new therapeutic options to treat leishmaniasis?

Leishmaniasis is a neglected disease, which needs improvements in drug development, mainly due to the toxicity, parasite resistance and low compliance of patients to treatment. Therefore, the development of new chemotherapeutic compounds is an urgent need. This opinion article will briefly highlight...

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Detalles Bibliográficos
Autores principales: ENNES-VIDAL, VITOR, MENNA-BARRETO, RUBEM FIGUEIREDO SADOCK, BRANQUINHA, MARTA HELENA, DOS SANTOS, ANDRÉ LUIS SOUZA, D'AVILA-LEVY, CLAUDIA MASINI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300003/
https://www.ncbi.nlm.nih.gov/pubmed/27869056
http://dx.doi.org/10.1017/S003118201600189X