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The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo

Mammalian development begins with segregation of the extra-embryonic trophectoderm from the embryonic lineage in the blastocyst. While cell polarity and adhesion play key roles, the decisive cue driving this lineage segregation remains elusive. Here, to study symmetry breaking, we use a reduced syst...

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Detalles Bibliográficos
Autores principales:	Korotkevich, Ekaterina, Niwayama, Ritsuya, Courtois, Aurélien, Friese, Stefanie, Berger, Nicolas, Buchholz, Frank, Hiiragi, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300053/ https://www.ncbi.nlm.nih.gov/pubmed/28171747 http://dx.doi.org/10.1016/j.devcel.2017.01.006

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