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Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials

Key disparities between the timing and methods of assessment in animal stroke studies and clinical trial may be part of the reason for the failure to translate promising findings. This study investigates the development of ischemic damage after thread occlusion MCAo in the rat, using histological an...

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Detalles Bibliográficos
Autores principales:	Rewell, Sarah S. J., Churilov, Leonid, Sidon, T. Kate, Aleksoska, Elena, Cox, Susan F., Macleod, Malcolm R., Howells, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300105/ https://www.ncbi.nlm.nih.gov/pubmed/28182727 http://dx.doi.org/10.1371/journal.pone.0171688

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