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Mechanism for generation of left isomerism in Ccdc40 mutant embryos
Leftward fluid flow in the mouse node is generated by cilia and is critical for initiating asymmetry of the left-right axis. Coiled-coil domain containing-40 (Ccdc40) plays an evolutionarily conserved role in the assembly of motile cilia and establishment of the left-right axis. Approximately one-th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300185/ https://www.ncbi.nlm.nih.gov/pubmed/28182636 http://dx.doi.org/10.1371/journal.pone.0171180 |