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320-row CT renal perfusion imaging in patients with aortic dissection: A preliminary study

OBJECTIVE: To investigate the clinical value of renal perfusion imaging in patients with aortic dissection (AD) using 320-row computed tomography (CT), and to determine the relationship between renal CT perfusion imaging and various factors of aortic dissection. METHODS: Forty-three patients with AD...

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Autores principales: Liu, Dongting, Liu, Jiayi, Wen, Zhaoying, Li, Yu, Sun, Zhonghua, Xu, Qin, Fan, Zhanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300209/
https://www.ncbi.nlm.nih.gov/pubmed/28182709
http://dx.doi.org/10.1371/journal.pone.0171235
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author Liu, Dongting
Liu, Jiayi
Wen, Zhaoying
Li, Yu
Sun, Zhonghua
Xu, Qin
Fan, Zhanming
author_facet Liu, Dongting
Liu, Jiayi
Wen, Zhaoying
Li, Yu
Sun, Zhonghua
Xu, Qin
Fan, Zhanming
author_sort Liu, Dongting
collection PubMed
description OBJECTIVE: To investigate the clinical value of renal perfusion imaging in patients with aortic dissection (AD) using 320-row computed tomography (CT), and to determine the relationship between renal CT perfusion imaging and various factors of aortic dissection. METHODS: Forty-three patients with AD who underwent 320-row CT renal perfusion before operation were prospectively enrolled in this study. Diagnosis of AD was confirmed by transthoracic echocardiography. Blood flow (BF) of bilateral renal perfusion was measured and analyzed. CT perfusion imaging signs of AD in relation to the type of AD, number of entry tears and the false lumen thrombus were observed and compared. RESULTS: The BF values of patients with type A AD were significantly lower than those of patients with type B AD (P = 0.004). No significant difference was found in the BF between different numbers of intimal tears (P = 0.288), but BF values were significantly higher in cases with a false lumen without thrombus and renal arteries arising from the true lumen than in those with thrombus (P = 0.036). The BF values measured between the true lumen, false lumen and overriding groups were different (P = 0.02), with the true lumen group having the highest. Also, the difference in BF values between true lumen and false lumen groups was statistically significant (P = 0.016), while no statistical significance was found in the other two groups (P > 0.05). The larger the size of intimal entry tears, the greater the BF values (P = 0.044). CONCLUSIONS: This study shows a direct correlation between renal CT perfusion changes and AD, with the size, number of intimal tears, different types of AD, different renal artery origins and false lumen thrombosis, significantly affecting the perfusion values.
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spelling pubmed-53002092017-02-28 320-row CT renal perfusion imaging in patients with aortic dissection: A preliminary study Liu, Dongting Liu, Jiayi Wen, Zhaoying Li, Yu Sun, Zhonghua Xu, Qin Fan, Zhanming PLoS One Research Article OBJECTIVE: To investigate the clinical value of renal perfusion imaging in patients with aortic dissection (AD) using 320-row computed tomography (CT), and to determine the relationship between renal CT perfusion imaging and various factors of aortic dissection. METHODS: Forty-three patients with AD who underwent 320-row CT renal perfusion before operation were prospectively enrolled in this study. Diagnosis of AD was confirmed by transthoracic echocardiography. Blood flow (BF) of bilateral renal perfusion was measured and analyzed. CT perfusion imaging signs of AD in relation to the type of AD, number of entry tears and the false lumen thrombus were observed and compared. RESULTS: The BF values of patients with type A AD were significantly lower than those of patients with type B AD (P = 0.004). No significant difference was found in the BF between different numbers of intimal tears (P = 0.288), but BF values were significantly higher in cases with a false lumen without thrombus and renal arteries arising from the true lumen than in those with thrombus (P = 0.036). The BF values measured between the true lumen, false lumen and overriding groups were different (P = 0.02), with the true lumen group having the highest. Also, the difference in BF values between true lumen and false lumen groups was statistically significant (P = 0.016), while no statistical significance was found in the other two groups (P > 0.05). The larger the size of intimal entry tears, the greater the BF values (P = 0.044). CONCLUSIONS: This study shows a direct correlation between renal CT perfusion changes and AD, with the size, number of intimal tears, different types of AD, different renal artery origins and false lumen thrombosis, significantly affecting the perfusion values. Public Library of Science 2017-02-09 /pmc/articles/PMC5300209/ /pubmed/28182709 http://dx.doi.org/10.1371/journal.pone.0171235 Text en © 2017 Liu et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Liu, Dongting
Liu, Jiayi
Wen, Zhaoying
Li, Yu
Sun, Zhonghua
Xu, Qin
Fan, Zhanming
320-row CT renal perfusion imaging in patients with aortic dissection: A preliminary study
title 320-row CT renal perfusion imaging in patients with aortic dissection: A preliminary study
title_full 320-row CT renal perfusion imaging in patients with aortic dissection: A preliminary study
title_fullStr 320-row CT renal perfusion imaging in patients with aortic dissection: A preliminary study
title_full_unstemmed 320-row CT renal perfusion imaging in patients with aortic dissection: A preliminary study
title_short 320-row CT renal perfusion imaging in patients with aortic dissection: A preliminary study
title_sort 320-row ct renal perfusion imaging in patients with aortic dissection: a preliminary study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300209/
https://www.ncbi.nlm.nih.gov/pubmed/28182709
http://dx.doi.org/10.1371/journal.pone.0171235
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