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Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver
Whole malaria sporozoite vaccine regimens are promising new strategies, and some candidates have demonstrated high rates of durable clinical protection associated with memory T cell responses. Little is known about the anatomical distribution of memory T cells following whole sporozoite vaccines, an...
Autores principales: | Pichyangkul, Sathit, Spring, Michele D., Yongvanitchit, Kosol, Kum-Arb, Utaiwan, Limsalakpetch, Amporn, Im-Erbsin, Rawiwan, Ubalee, Ratawan, Vanachayangkul, Pattaraporn, Remarque, Edmond J., Angov, Evelina, Smith, Philip L., Saunders, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300246/ https://www.ncbi.nlm.nih.gov/pubmed/28182750 http://dx.doi.org/10.1371/journal.pone.0171826 |
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