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Benefits and unintended consequences of antimicrobial de-escalation: Implications for stewardship programs

Sequential antimicrobial de-escalation aims to minimize resistance to high-value broad-spectrum empiric antimicrobials by switching to alternative drugs when testing confirms susceptibility. Though widely practiced, the effects de-escalation are not well understood. Definitions of interventions and...

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Detalles Bibliográficos
Autores principales: Hughes, Josie, Huo, Xi, Falk, Lindsey, Hurford, Amy, Lan, Kunquan, Coburn, Bryan, Morris, Andrew, Wu, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300270/
https://www.ncbi.nlm.nih.gov/pubmed/28182774
http://dx.doi.org/10.1371/journal.pone.0171218