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Benefits and unintended consequences of antimicrobial de-escalation: Implications for stewardship programs
Sequential antimicrobial de-escalation aims to minimize resistance to high-value broad-spectrum empiric antimicrobials by switching to alternative drugs when testing confirms susceptibility. Though widely practiced, the effects de-escalation are not well understood. Definitions of interventions and...
Autores principales: | Hughes, Josie, Huo, Xi, Falk, Lindsey, Hurford, Amy, Lan, Kunquan, Coburn, Bryan, Morris, Andrew, Wu, Jianhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300270/ https://www.ncbi.nlm.nih.gov/pubmed/28182774 http://dx.doi.org/10.1371/journal.pone.0171218 |
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