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Pyoderma Gangrenosum of the breast: A case report study

INTRODUCTION: Pyoderma gangrenosum (PG) of the breast is a rare and rapidly spreading disease, which usually co-exists with severe underlying systemic conditions. PG often presents secondary to breast surgery with skin lesions and signs of infection, even though it is a non-infectious, necrotizing d...

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Autores principales: Marinopoulos, Spyridon, Theofanakis, Charalampos, Zacharouli, Theoni, Sotiropoulou, Maria, Dimitrakakis, Constantine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300301/
https://www.ncbi.nlm.nih.gov/pubmed/28187399
http://dx.doi.org/10.1016/j.ijscr.2017.01.036
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author Marinopoulos, Spyridon
Theofanakis, Charalampos
Zacharouli, Theoni
Sotiropoulou, Maria
Dimitrakakis, Constantine
author_facet Marinopoulos, Spyridon
Theofanakis, Charalampos
Zacharouli, Theoni
Sotiropoulou, Maria
Dimitrakakis, Constantine
author_sort Marinopoulos, Spyridon
collection PubMed
description INTRODUCTION: Pyoderma gangrenosum (PG) of the breast is a rare and rapidly spreading disease, which usually co-exists with severe underlying systemic conditions. PG often presents secondary to breast surgery with skin lesions and signs of infection, even though it is a non-infectious, necrotizing dermatological entity. PRESENTATION OF CASE: We present a case of de novo unilateral breast PG in 37-year-old woman, with a clear medical history whatsoever. The patient was treated with corticosteroids and, in a two-month follow up, presents with nearly no signs of PG. DISCUSSION: PG of the breast presents with atypical clinical signs and is characterized by an exclusion-based diagnosis. It often mimics inflammation but is resistant to antibiotics. CONCLUSION: The optimal treatment for PG is systemic use of corticosteroids and surgical debridement of the necrotic tissue, while the timely onset of the therapeutic approach is of outmost importance.
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spelling pubmed-53003012017-02-17 Pyoderma Gangrenosum of the breast: A case report study Marinopoulos, Spyridon Theofanakis, Charalampos Zacharouli, Theoni Sotiropoulou, Maria Dimitrakakis, Constantine Int J Surg Case Rep Case Report INTRODUCTION: Pyoderma gangrenosum (PG) of the breast is a rare and rapidly spreading disease, which usually co-exists with severe underlying systemic conditions. PG often presents secondary to breast surgery with skin lesions and signs of infection, even though it is a non-infectious, necrotizing dermatological entity. PRESENTATION OF CASE: We present a case of de novo unilateral breast PG in 37-year-old woman, with a clear medical history whatsoever. The patient was treated with corticosteroids and, in a two-month follow up, presents with nearly no signs of PG. DISCUSSION: PG of the breast presents with atypical clinical signs and is characterized by an exclusion-based diagnosis. It often mimics inflammation but is resistant to antibiotics. CONCLUSION: The optimal treatment for PG is systemic use of corticosteroids and surgical debridement of the necrotic tissue, while the timely onset of the therapeutic approach is of outmost importance. Elsevier 2017-01-24 /pmc/articles/PMC5300301/ /pubmed/28187399 http://dx.doi.org/10.1016/j.ijscr.2017.01.036 Text en © 2017 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Marinopoulos, Spyridon
Theofanakis, Charalampos
Zacharouli, Theoni
Sotiropoulou, Maria
Dimitrakakis, Constantine
Pyoderma Gangrenosum of the breast: A case report study
title Pyoderma Gangrenosum of the breast: A case report study
title_full Pyoderma Gangrenosum of the breast: A case report study
title_fullStr Pyoderma Gangrenosum of the breast: A case report study
title_full_unstemmed Pyoderma Gangrenosum of the breast: A case report study
title_short Pyoderma Gangrenosum of the breast: A case report study
title_sort pyoderma gangrenosum of the breast: a case report study
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300301/
https://www.ncbi.nlm.nih.gov/pubmed/28187399
http://dx.doi.org/10.1016/j.ijscr.2017.01.036
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