The Atypical Ubiquitin E2 Conjugase UBE2L3 Is an Indirect Caspase-1 Target and Controls IL-1β Secretion by Inflammasomes

Caspase-1 activation by inflammasome signaling scaffolds initiates inflammation and antimicrobial responses. Caspase-1 proteolytically converts newly induced pro-interleukin 1 beta (IL-1β) into its mature form and directs its secretion, triggering pyroptosis and release of non-substrate alarmins suc...

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Detalles Bibliográficos
Autores principales: Eldridge, Matthew J.G., Sanchez-Garrido, Julia, Hoben, Gil Ferreira, Goddard, Philippa J., Shenoy, Avinash R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300903/
https://www.ncbi.nlm.nih.gov/pubmed/28147281
http://dx.doi.org/10.1016/j.celrep.2017.01.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300903/
https://www.ncbi.nlm.nih.gov/pubmed/28147281
http://dx.doi.org/10.1016/j.celrep.2017.01.015

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