Cargando…

IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of Adult T-cell Leukemia/Lymphoma patients

Detalles Bibliográficos
Autores principales:	Dierckx, T, Khouri, R, Menezes, S M, Decanine, D, Farre, L, Bittencourt, A, Vandamme, A M, Van Weyenbergh, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301034/ https://www.ncbi.nlm.nih.gov/pubmed/28128792 http://dx.doi.org/10.1038/bcj.2016.126

Ejemplares similares

Superior antiviral and antiproliferative activity of IFN-beta vs. IFN-alpha in primary ATL cells occurs downstream of STAT1 signaling
por: Khouri, Ricardo, et al.
Publicado: (2014)

A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients
por: Khouri, Ricardo, et al.
Publicado: (2018)

Ascorbic acid has superior antiviral and antiproliferative effects over IFN-alpha in HAM/TSP PBMC ex vivo
por: Moens, Britta, et al.
Publicado: (2011)

Ascorbic Acid Has Superior Ex Vivo Antiproliferative, Cell Death-Inducing and Immunomodulatory Effects over IFN-α in HTLV-1-Associated Myelopathy
por: Moens, Britta, et al.
Publicado: (2012)

Decreased RORC expression and downstream signaling in HTLV‐1‐associated adult T‐cell lymphoma/leukemia uncovers an antiproliferative IL17 link: A potential target for immunotherapy?
por: Subramanian, Kritika, et al.
Publicado: (2018)

B cell costimulatory molecules as potential biomarkers in HAM/TSP
por: Menezes, Soraya M, et al.
Publicado: (2011)

Chalcone Methoxy Derivatives Exhibit Antiproliferative and Proapoptotic Activity on Canine Lymphoma and Leukemia Cells
por: Pawlak, Aleksandra, et al.
Publicado: (2020)

Monocyte accumulation is an early event in HAM/TSP pathogenesis, while monocyte activation and IFN-regulated gene expression persist in chronic HAM/TSP
por: Menezes, Soraya Maria, et al.
Publicado: (2015)

Endogenous IFNβ expression predicts outcome in critical patients with COVID-19
por: Menezes, Soraya Maria, et al.
Publicado: (2021)

A selective defect in Fas-mediated apoptosis in HAM/TSP: An ex vivo, in vitro and in silico study
por: Menezes, Soraya Maria, et al.
Publicado: (2014)

Inhibiting autophagy potentiates the anticancer activity of IFN1@/IFNα in chronic myeloid leukemia cells
por: Zhu, Shan, et al.
Publicado: (2013)

Comprehensive Antiretroviral Restriction Factor Profiling Reveals the Evolutionary Imprint of the ex Vivo and in Vivo IFN-β Response in HTLV-1-Associated Neuroinflammation
por: Leal, Fabio E., et al.
Publicado: (2018)

XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis
por: Boons, Eline, et al.
Publicado: (2021)

IFNα and IFNγ Impede Marek’s Disease Progression
por: Bertzbach, Luca D., et al.
Publicado: (2019)

Aberrant cell signalling in PBMCs upon IFN‐α stimulation in primary Sjögren's syndrome patients associates with type I interferon signature
por: Davies, Richard, et al.
Publicado: (2018)

IL6 sensitizes prostate cancer to the antiproliferative effect of IFNα(2) through IRF9
por: Erb, Holger H H, et al.
Publicado: (2013)

Differential regulation of IFNα, IFNβ and IFNε gene expression in human cervical epithelial cells
por: Couret, Jennifer, et al.
Publicado: (2017)

IL-6/IFN-γ double knockdown CAR-T cells reduce the release of multiple cytokines from PBMCs in vitro
por: Zhang, Huihui, et al.
Publicado: (2022)

Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma
por: Jin, L, et al.
Publicado: (2011)

Endothelin-receptor antagonists are proapoptotic and antiproliferative in human colon cancer cells
por: Peduto Eberl, L, et al.
Publicado: (2003)

Antiproliferative and proapoptotic effects of DODAC/synthetic phosphoethanolamine on hepatocellular carcinoma cells
por: Luna, Arthur Cássio de Lima, et al.
Publicado: (2018)

A Comprehensive Assessment of Apigenin as an Antiproliferative, Proapoptotic, Antiangiogenic and Immunomodulatory Phytocompound
por: Ghițu, Alexandra, et al.
Publicado: (2019)

Antiproliferative effects of sorafenib and pegylated IFN-α2b on human liver cancer cells in vitro and in vivo
por: KUSANO, HIRONORI, et al.
Publicado: (2013)

Context Is Key: Delineating the Unique Functions of IFNα and IFNβ in Disease
por: Fox, Lindsey E., et al.
Publicado: (2020)

HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients
por: Brochado, Óscar, et al.
Publicado: (2021)

Global DNA Methylation and Hydroxymethylation Levels in PBMCs Are Altered in RRMS Patients Treated with IFN-β and GA—A Preliminary Study
por: Reyes-Mata, María Paulina, et al.
Publicado: (2023)

TP53 and p16INK4A mutations in adult-T cell leukemia/lymphoma (ATL) in Bahia (Brazil)
por: Magalhães, Marcelo, et al.
Publicado: (2011)

Characteristics of oligodeoxyribonucleotides that induce interferon (IFN)-α in the pig and the phenotype of the IFN-α producing cells
por: Domeika, Kristina, et al.
Publicado: (2004)

Antiviral, Immunomodulatory and Antiproliferative Activities of Recombinant Soluble IFNAR2 without IFN-ß Mediation
por: Hurtado-Guerrero, Isaac, et al.
Publicado: (2020)

An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans
por: Delgobo, Murilo, et al.
Publicado: (2019)

Baseline IFN-γ and IL-10 expression in PBMCs could predict response to PD-1 checkpoint inhibitors in advanced melanoma patients
por: Giunta, Emilio Francesco, et al.
Publicado: (2020)

IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies
por: Duong, Francois H.T., et al.
Publicado: (2014)

Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection
por: Echebli, Nadia, et al.
Publicado: (2018)

IFN-α suppresses HTLV-1 expression via PKR in infected cells and renders them susceptible to AZT through p53 activation in AZT/IFN-α treatment
por: Kinpara, Shuichi, et al.
Publicado: (2014)

Antiviral Activity of Porcine IFN-λ3 and IFN-α against Porcine Rotavirus In Vitro
por: Deng, Lishuang, et al.
Publicado: (2022)

Tomentosin a Sesquiterpene Lactone Induces Antiproliferative and Proapoptotic Effects in Human Burkitt Lymphoma by Deregulation of Anti- and Pro-Apoptotic Genes
por: Virdis, Patrizia, et al.
Publicado: (2021)

Simultaneous RNA quantification of human and retroviral genomes reveals intact interferon signaling in HTLV-1-infected CD4+ T cell lines
por: Moens, Britta, et al.
Publicado: (2012)

Comparative Multi-Donor Study of IFNγ Secretion and Expression by Human PBMCs Using ELISPOT Side-by-Side with ELISA and Flow Cytometry Assays
por: Hagen, Jodi, et al.
Publicado: (2015)

Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1
por: Datta, Sibnarayan, et al.
Publicado: (2011)

CD80(+) and CD86(+) B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis
por: Menezes, Soraya Maria, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8t539bggusm3o6igdmi1up399c