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The combination of the functionalities of feedback circuits is determinant for the attractors’ number and size in pathway-like Boolean networks
Molecular regulation was initially assumed to follow both a unidirectional and a hierarchical organization forming pathways. Regulatory processes, however, form highly interlinked networks with non-hierarchical and non-unidirectional structures that contain statistically overrepresented circuits or...
Autores principales: | Azpeitia, Eugenio, Muñoz, Stalin, González-Tokman, Daniel, Martínez-Sánchez, Mariana Esther, Weinstein, Nathan, Naldi, Aurélien, Álvarez-Buylla, Elena R., Rosenblueth, David A., Mendoza, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301197/ https://www.ncbi.nlm.nih.gov/pubmed/28186191 http://dx.doi.org/10.1038/srep42023 |
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