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The combination of the functionalities of feedback circuits is determinant for the attractors’ number and size in pathway-like Boolean networks

Molecular regulation was initially assumed to follow both a unidirectional and a hierarchical organization forming pathways. Regulatory processes, however, form highly interlinked networks with non-hierarchical and non-unidirectional structures that contain statistically overrepresented circuits or...

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Detalles Bibliográficos
Autores principales: Azpeitia, Eugenio, Muñoz, Stalin, González-Tokman, Daniel, Martínez-Sánchez, Mariana Esther, Weinstein, Nathan, Naldi, Aurélien, Álvarez-Buylla, Elena R., Rosenblueth, David A., Mendoza, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301197/
https://www.ncbi.nlm.nih.gov/pubmed/28186191
http://dx.doi.org/10.1038/srep42023

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