Preclinical evaluation of bacterially produced RSV-G protein vaccine: Strong protection against RSV challenge in cotton rat model

In current study, we evaluated the safety and protective efficacy of recombinant unglycosylated RSV G protein ectodomain produced in E. coli (in presence and absence of oil-in-water adjuvant) in a preclinical RSV susceptible cotton rat challenge model compared to formaldehyde inactivated RSV (FI-RSV...

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Detalles Bibliográficos
Autores principales: Fuentes, Sandra, Klenow, Laura, Golding, Hana, Khurana, Surender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301242/
https://www.ncbi.nlm.nih.gov/pubmed/28186208
http://dx.doi.org/10.1038/srep42428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301242/
https://www.ncbi.nlm.nih.gov/pubmed/28186208
http://dx.doi.org/10.1038/srep42428

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