Dysregulated autophagy increased melanocyte sensitivity to H(2)O(2)-induced oxidative stress in vitiligo

In vitiligo, melanocytes are particularly vulnerable to oxidative stress owing to the pro-oxidant state generated during melanin synthesis and to the genetic antioxidant defects. Autophagy is a controlled self-digestion process which can protect cells against oxidative damage. However, the exact rol...

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Detalles Bibliográficos
Autores principales: He, Yuanmin, Li, Shuli, Zhang, Weigang, Dai, Wei, Cui, Tingting, Wang, Gang, Gao, Tianwen, Li, Chunying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301258/
https://www.ncbi.nlm.nih.gov/pubmed/28186139
http://dx.doi.org/10.1038/srep42394

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