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Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases

Class I phosphoinositide 3-kinase (PI3K) generates phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) at the plasma membrane in response to growth factors, activating a signalling cascade that regulates many cellular functions including cell growth, proliferation, survival, migration and m...

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Detalles Bibliográficos
Autores principales:	Rodgers, Samuel J., Ferguson, Daniel T., Mitchell, Christina A., Ooms, Lisa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301276/ https://www.ncbi.nlm.nih.gov/pubmed/28082369 http://dx.doi.org/10.1042/BSR20160432

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