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SEPIa, a knowledge-driven algorithm for predicting conformational B-cell epitopes from the amino acid sequence

BACKGROUND: The identification of immunogenic regions on the surface of antigens, which are able to be recognized by antibodies and to trigger an immune response, is a major challenge for the design of new and effective vaccines. The prediction of such regions through computational immunology techni...

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Detalles Bibliográficos
Autores principales: Dalkas, Georgios A., Rooman, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301386/
https://www.ncbi.nlm.nih.gov/pubmed/28183272
http://dx.doi.org/10.1186/s12859-017-1528-9