Inhibition of Receptor-Interacting Protein Kinase 1 with Necrostatin–1s ameliorates disease progression in elastase-induced mouse abdominal aortic aneurysm model

Abdominal aortic aneurysm (AAA) is a common aortic disease with a progressive nature. There is no approved pharmacological treatment to effectively slow aneurysm growth or prevent rupture. Necroptosis is a form of programmed necrosis that is regulated by receptor-interacting protein kinases (RIPs)....

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Detalles Bibliográficos
Autores principales: Wang, Qiwei, Zhou, Ting, Liu, Zhenjie, Ren, Jun, Phan, Noel, Gupta, Kartik, Stewart, Danielle M., Morgan, Stephanie, Assa, Carmel, Kent, K. Craig, Liu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301478/
https://www.ncbi.nlm.nih.gov/pubmed/28186202
http://dx.doi.org/10.1038/srep42159

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