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Targeting of phage particles towards endothelial cells by antibodies selected through a multi-parameter selection strategy
One of the hallmarks of cancer is sustained angiogenesis. Here, normal endothelial cells are activated, and their formation of new blood vessels leads to continued tumour growth. An improved patient condition is often observed when angiogenesis is prevented or normalized through targeting of these g...
Autores principales: | Mandrup, Ole A., Lykkemark, Simon, Kristensen, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301479/ https://www.ncbi.nlm.nih.gov/pubmed/28186116 http://dx.doi.org/10.1038/srep42230 |
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