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The Proteasome Inhibition Model of Parkinson’s Disease

The pathological hallmarks of Parkinson’s disease are the progressive loss of nigral dopaminergic neurons and the formation of intracellular inclusion bodies, termed Lewy bodies, in surviving neurons. Accumulation of proteins in large insoluble cytoplasmic aggregates has been proposed to result, par...

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Detalles Bibliográficos
Autores principales:	Bentea, Eduard, Verbruggen, Lise, Massie, Ann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302045/ https://www.ncbi.nlm.nih.gov/pubmed/27802243 http://dx.doi.org/10.3233/JPD-160921

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