A multi-stage drop-the-losers design for multi-arm clinical trials

Multi-arm multi-stage trials can improve the efficiency of the drug development process when multiple new treatments are available for testing. A group-sequential approach can be used in order to design multi-arm multi-stage trials, using an extension to Dunnett’s multiple-testing procedure. The act...

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Detalles Bibliográficos
Autores principales: Wason, James, Stallard, Nigel, Bowden, Jack, Jennison, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302074/
https://www.ncbi.nlm.nih.gov/pubmed/25228636
http://dx.doi.org/10.1177/0962280214550759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302074/
https://www.ncbi.nlm.nih.gov/pubmed/25228636
http://dx.doi.org/10.1177/0962280214550759

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