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An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins
Peroxiredoxins (Prxs or Prdxs) are a large protein superfamily of antioxidant enzymes that rapidly detoxify damaging peroxides and/or affect signal transduction and, thus, have roles in proliferation, differentiation, and apoptosis. Prx superfamily members are widespread across phylogeny and multipl...
Autores principales: | Harper, Angela F., Leuthaeuser, Janelle B., Babbitt, Patricia C., Morris, John H., Ferrin, Thomas E., Poole, Leslie B., Fetrow, Jacquelyn S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302317/ https://www.ncbi.nlm.nih.gov/pubmed/28187133 http://dx.doi.org/10.1371/journal.pcbi.1005284 |
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