A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Compound in Comparison to Cisplatin

Many clinically available anticancer compounds are designed to target DNA. This commonality of action often yields overlapping cellular response mechanisms and can thus detract from drug efficacy. New compounds are required to overcome resistance mechanisms that effectively neutralise compounds like...

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Detalles Bibliográficos
Autores principales: Wright, Elise P., Padula, Matthew P., Higgins, Vincent J., Aldrich-Wright, Janice R., Coorssen, Jens R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302693/
https://www.ncbi.nlm.nih.gov/pubmed/28250393
http://dx.doi.org/10.3390/proteomes2040501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302693/
https://www.ncbi.nlm.nih.gov/pubmed/28250393
http://dx.doi.org/10.3390/proteomes2040501

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