Distinct antibody responses of patients with mild and severe leptospirosis determined by whole proteome microarray analysis

BACKGROUND: Leptospirosis is an important zoonotic disease worldwide. Humans usually present a mild non-specific febrile illness, but a proportion of them develop more severe outcomes, such as multi-organ failure, lung hemorrhage and death. Such complications are thought to depend on several factors...

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Detalles Bibliográficos
Autores principales: Lessa-Aquino, Carolina, Lindow, Janet C., Randall, Arlo, Wunder, Elsio, Pablo, Jozelyn, Nakajima, Rie, Jasinskas, Algis, Cruz, Jaqueline S., Damião, Alcineia O., Nery, Nívison, Ribeiro, Guilherme S., Costa, Federico, Hagan, José E., Reis, Mitermayer Galvão, Ko, Albert I., Medeiros, Marco Alberto, Felgner, Philip L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302828/
https://www.ncbi.nlm.nih.gov/pubmed/28141801
http://dx.doi.org/10.1371/journal.pntd.0005349

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