Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors

Human papilloma virus (HPV)-associated head and neck squamous cell carcinoma (HNSCC) has a better prognosis than it's HPV negative (HPV(−)) counterpart. This may be due to the higher numbers of tumor-infiltrating lymphocytes (TILs) in HPV positive (HPV(+)) tumors. RNA-Sequencing (RNA-Seq) was u...

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Detalles Bibliográficos
Autores principales: Wood, Oliver, Woo, Jeongmin, Seumois, Gregory, Savelyeva, Natalia, McCann, Katy J., Singh, Divya, Jones, Terry, Peel, Lailah, Breen, Michael S., Ward, Matthew, Martin, Eva Garrido, Sanchez-Elsner, Tilman, Thomas, Gareth, Vijayanand, Pandurangan, Woelk, Christopher H., King, Emma, Ottensmeier, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302866/
https://www.ncbi.nlm.nih.gov/pubmed/27462861
http://dx.doi.org/10.18632/oncotarget.10788

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