Targeting Zfp148 activates p53 and reduces tumor initiation in the gut

The transcription factor Zinc finger protein 148 (Zfp148, ZBP-89, BFCOL, BERF1, htβ) interacts physically with the tumor suppressor p53, but the significance of this interaction is not known. We recently showed that knockout of Zfp148 in mice leads to ectopic activation of p53 in some tissues and cu...

Descripción completa

Detalles Bibliográficos
Autores principales: Nilton, Anna, Sayin, Volkan I., Zou, Zhiyuan V., Sayin, Sama I., Bondjers, Cecilia, Gul, Nadia, Agren, Pia, Fogelstrand, Per, Nilsson, Ola, Bergo, Martin O., Lindahl, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302905/
https://www.ncbi.nlm.nih.gov/pubmed/27487143
http://dx.doi.org/10.18632/oncotarget.10899

Ejemplares similares

Ejemplares similares