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Nuclear IKKα mediates microRNA-7/-103/107/21 inductions to downregulate maspin expression in response to HBx overexpression
Maspin is a tumor suppressor that stimulates apoptosis and inhibits metastasis in various cancer types, including hepatocellular carcinoma (HCC). Our previous study has demonstrated that HBx induced microRNA-7, 103, 107, and 21 expressions to suppress maspin expression, leading to metastasis, chemor...
Autores principales: | Chen, Wen-Shu, Liu, Liang-Chih, Yen, Chia-Jui, Chen, Yun-Ju, Chen, Jhen-Yu, Ho, Chien-Yi, Liu, Shu-Hui, Chen, Ching-Chow, Huang, Wei-Chien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302916/ https://www.ncbi.nlm.nih.gov/pubmed/27409165 http://dx.doi.org/10.18632/oncotarget.10462 |
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