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Intratumoral heterogeneity of the therapeutical response to gemcitabine and metformin

Cancer heterogeneity and microenvironmental aspects within a tumor are considered key factors influencing resistance of carcinoma cells to distinct chemotherapeutical agents. We evaluated a high concentration of metformin in combination with gemcitabine on a syngeneic orthotopic mouse model using 66...

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Detalles Bibliográficos
Autores principales:	Zechner, Dietmar, Bürtin, Florian, Albert, Ann-Christin, Zhang, Xianbin, Kumstel, Simone, Schönrogge, Maria, Graffunder, Josefine, Shih, Hao-Yu, Müller, Sarah, Radecke, Tobias, Jaster, Robert, Vollmar, Brigitte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302922/ https://www.ncbi.nlm.nih.gov/pubmed/27486761 http://dx.doi.org/10.18632/oncotarget.10892

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