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Met promotes the formation of double minute chromosomes induced by Sei-1 in NIH-3T3 murine fibroblasts

BACKGROUND: Sei-1 is an oncogene capable of inducing double minute chromosomes (DMs) formation. DMs are hallmarks of amplification and contribute to oncogenesis. However, the mechanism of Sei-1 inducing DMs formation remains unelucidated. RESULTS: DMs formation significantly increased during serial...

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Detalles Bibliográficos
Autores principales: Bao, Yantao, Liu, Jia, You, Jia, Wu, Di, Yu, Yang, Liu, Chang, Wang, Lei, Wang, Fei, Xu, Lu, Wang, Liqun, Wang, Nan, Tian, Xing, Wang, Falin, Liang, Hongbin, Gao, Yating, Cui, Xiaobo, Ji, Guohua, Bai, Jing, Yu, Jingcui, Meng, Xiangning, Jin, Yan, Sun, Wenjing, Guan, Xin-yuan, Zhang, Chunyu, Fu, Songbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302943/
https://www.ncbi.nlm.nih.gov/pubmed/27494853
http://dx.doi.org/10.18632/oncotarget.10994