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Ablation of human telomerase reverse transcriptase (hTERT) induces cellular senescence in gastric cancer through a galectin-3 dependent mechanism
The human Telomerase Reverse Transcriptase (hTERT) gene encodes a rate-limiting catalytic subunit of telomerase that maintains genomic integrity. Suppression of hTERT expression could induce cellular senescence and is considered a potent approach for gastric cancer therapy. However, control of hTERT...
Autores principales: | La, Sun-Hyuk, Kim, Seok-Jun, Kang, Hyeok-Gu, Lee, Han-Woong, Chun, Kyung-Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302977/ https://www.ncbi.nlm.nih.gov/pubmed/27494887 http://dx.doi.org/10.18632/oncotarget.10986 |
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