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uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy
There is strong evidence supporting the role of the plasminogen activator system in head and neck squamous cell carcinoma (HNSCC), particularly of its uPA (urokinase plasminogen activator) / uPAR (urokinase plasminogen activator receptor) and SERPINE1 components. Overexpression of uPA/uPAR and SERPI...
Autores principales: | Pavón, Miguel Angel, Arroyo-Solera, Irene, Céspedes, Maria Virtudes, Casanova, Isolda, León, Xavier, Mangues, Ramón |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302994/ https://www.ncbi.nlm.nih.gov/pubmed/27385000 http://dx.doi.org/10.18632/oncotarget.10344 |
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