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Potential role of the N-MYC downstream-regulated gene family in reprogramming cancer metabolism under hypoxia

Metabolic reprogramming toward aerobic glycolysis and lactate fermentation supplies cancer cells with intermediate metabolites, which are used as macromolecule precursors. The oncogene MYC contributes to such aerobic metabolism by activating the expression of numerous genes essential for glycolysis...

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Detalles Bibliográficos
Autores principales:	Lee, Ga Young, Chun, Yang-Sook, Shin, Hyun-Woo, Park, Jong-Wan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303000/ https://www.ncbi.nlm.nih.gov/pubmed/27447861 http://dx.doi.org/10.18632/oncotarget.10684

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