Cargando…

Regulatory role of cytosolic phospholipase A(2) alpha in the induction of CD40 in microglia

BACKGROUND: The aberrant expression of CD40, a co-stimulatory receptor found on the antigen-presenting cells, is involved in the pathogenesis of various degenerative diseases. Our previous study demonstrated that the reduction of cytosolic phospholipase A(2) alpha (cPLA(2)α) protein overexpression a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Malada-Edelstein, Yafa Fetfet, Hadad, Nurit, Levy, Rachel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303221/ https://www.ncbi.nlm.nih.gov/pubmed/28187742 http://dx.doi.org/10.1186/s12974-017-0811-z

Ejemplares similares

Early upregulation of cytosolic phospholipase A(2)α in motor neurons is induced by misfolded SOD1 in a mouse model of amyotrophic lateral sclerosis
por: Malada Edelstein, Yafa Fetfet, et al.
Publicado: (2021)

Reduction of cytosolic phospholipase A(2)α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis
por: Solomonov, Yulia, et al.
Publicado: (2016)

Induction of Cytosolic Phospholipase A(2)α Is Required for Adipose Neutrophil Infiltration and Hepatic Insulin Resistance Early in the Course of High-Fat Feeding
por: Hadad, Nurit, et al.
Publicado: (2013)

Unique targeting of cytosolic phospholipase A(2) to plasma membranes mediated by the NADPH oxidase in phagocytes
por: Shmelzer, Zeev, et al.
Publicado: (2003)

Study of the Role of Cytosolic Phospholipase A(2) Alpha in Eicosanoid Generation and Thymocyte Maturation in the Thymus
por: Rousseau, Matthieu, et al.
Publicado: (2015)

The Step Further to Understand the Role of Cytosolic Phospholipase A(2) Alpha and Group X Secretory Phospholipase A(2) in Allergic Inflammation: Pilot Study
por: Pniewska, Ewa, et al.
Publicado: (2014)

Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells
por: Tunset, Hanna Maja, et al.
Publicado: (2019)

Cytosolic Phospholipase A2 and Lysophospholipids in Tumor Angiogenesis
por: Linkous, Amanda G., et al.
Publicado: (2010)

Cytosolic Phospholipase A(2) alpha/Arachidonic Acid Signaling Mediates Depolarization-Induced Suppression of Excitation in the Cerebellum
por: Wang, De-Juan, et al.
Publicado: (2012)

Discrete Role for Cytosolic Phospholipase A(2)α in Platelets: Studies Using Single and Double Mutant Mice of Cytosolic and Group IIA Secretory Phospholipase A(2)
por: Wong, Dennis A., et al.
Publicado: (2002)

Cyclooxygenase-2 and Cytosolic Phospholipase A2 Are Overexpressed in Mucinous Pancreatic Cysts
por: Mensah, Elsie T., et al.
Publicado: (2019)

Correction: Cytosolic Phospholipase A(2) alpha/Arachidonic Acid Signaling Mediates Depolarization-Induced Suppression of Excitation in the Cerebellum
por: Wang, De-Juan, et al.
Publicado: (2012)

Cytosolic Phospholipase A2 Modulates TLR2 Signaling in Synoviocytes
por: Sommerfelt, Randi M., et al.
Publicado: (2015)

Role of Phosphorylation Sites and the C2 Domain in Regulation of Cytosolic Phospholipase A(2)
por: Gijón, Miguel A., et al.
Publicado: (1999)

Lumenato protects normal human dermal fibroblasts from neutrophil-induced collagen-3 damage in co-cultures
por: Solomonov, Yulia, et al.
Publicado: (2021)

Prognostic significance of cytosolic phospholipase A2 expression in patients with colorectal cancer
por: Yoo, Young Sun, et al.
Publicado: (2011)

Cytosolic phospholipase A2 regulation in the hibernating thirteen-lined ground squirrel
por: Woods, Ashley K., et al.
Publicado: (2007)

Functions and mechanisms of cytosolic phospholipase A(2) in central nervous system trauma
por: Zhang, Hao-Jie, et al.
Publicado: (2022)

Predominant Role of Cytosolic Phospholipase A(2)α in Dioxin-induced Neonatal Hydronephrosis in Mice
por: Yoshioka, Wataru, et al.
Publicado: (2014)

Protective Effect of Cytosolic Phospholipase A2 Inhibition against Inflammation and Degeneration by Promoting Regulatory T Cells in Rats with Experimental Autoimmune Encephalomyelitis
por: Yang, Dan, et al.
Publicado: (2014)

Astrocyte Inositol Triphosphate Receptor Type 2 and Cytosolic Phospholipase A(2) Alpha Regulate Arteriole Responses in Mouse Neocortical Brain Slices
por: He, Lihua, et al.
Publicado: (2012)

Cytosolic phospholipase A(2 )alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice
por: Kishimoto, Koji, et al.
Publicado: (2010)

Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis
por: Marusic, Suzana, et al.
Publicado: (2005)

Cytosolic Phospholipase A(2)α–deficient Mice Are Resistant to Collagen-induced Arthritis
por: Hegen, Martin, et al.
Publicado: (2003)

Pharmacophore-based discovery of a novel cytosolic phospholipase A(2)α inhibitor
por: Noha, Stefan M., et al.
Publicado: (2012)

Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
por: Mahammad, Nur, et al.
Publicado: (2021)

Renal tubular injury induced by glyphosate combined with hard water: the role of cytosolic phospholipase A2
por: Wang, Ruojing, et al.
Publicado: (2021)

Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson's disease alpha-synuclein transgenic mice
por: Ye, Minsook, et al.
Publicado: (2016)

Pathways Regulating Cytosolic Phospholipase A(2) Activation and Eicosanoid Production in Macrophages by Candida albicans
por: Suram, Saritha, et al.
Publicado: (2010)

Cytosolic Phospholipase A2 Regulates TNF-Induced Production of Joint Destructive Effectors in Synoviocytes
por: Sommerfelt, Randi M., et al.
Publicado: (2013)

Cytosolic Phospholipase A(2) Protein as a Novel Therapeutic Target for Spinal Cord Injury
por: Liu, Nai-Kui, et al.
Publicado: (2014)

Structural basis of phosphatidylcholine recognition by the C2–domain of cytosolic phospholipase A(2)α
por: Hirano, Yoshinori, et al.
Publicado: (2019)

Phospholipase D Family Member 4, a Transmembrane Glycoprotein with No Phospholipase D Activity, Expression in Spleen and Early Postnatal Microglia
por: Yoshikawa, Fumio, et al.
Publicado: (2010)

An Essential Role of Cytosolic Phospholipase A2α in Prostaglandin E2–mediated Bone Resorption Associated with Inflammation
por: Miyaura, Chisato, et al.
Publicado: (2003)

Cytosolic PhospholipaseA2 Inhibition with PLA-695 Radiosensitizes Tumors in Lung Cancer Animal Models
por: Thotala, Dinesh, et al.
Publicado: (2013)

Cytosolic phospholipase A(2) contributes to innate immune defense against Candida albicans lung infection
por: Jayaraja, Sabarirajan, et al.
Publicado: (2016)

Highly Potent 2-Oxoester Inhibitors of Cytosolic Phospholipase A(2) (GIVA cPLA(2))
por: Psarra, Anastasia, et al.
Publicado: (2018)

Cytosolic Phospholipase A2 Is Required for Fexofenadine’s Therapeutic Effects against Inflammatory Bowel Disease in Mice
por: Zhao, Xiangli, et al.
Publicado: (2021)

Correction: Structural basis of phosphatidylcholine recognition by the C2-Domain of cytosolic phospholipase A(2)α
por: Hirano, Yoshinori, et al.
Publicado: (2021)

Singapore Grouper Iridovirus Disturbed Glycerophospholipids Homeostasis: Cytosolic Phospholipase A2 Was Essential for Virus Replication
por: Ni, Na, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mapsh58f3kjl512bj7oej976ku