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Strontium ranelate causes osteophytes overgrowth in a model of early phase osteoarthritis

BACKGROUND: Osteoarthritis (OA) involves cartilage changes as well as modifications of subchondral bone and synovial tissues. Strontium ranelate (SR), an anti-osteoporosis compound, which is currently in phase III clinical trial for treatment of OA. Evidences suggest that SR preferably deposited in...

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Detalles Bibliográficos
Autores principales:	Chu, Jian-Guo, Dai, Mu-Wei, Wang, Yu, Tian, Fa-Ming, Song, Hui-Ping, Xiao, Ya-Ping, Shao, Li-Tao, Zhang, Ying-Ze, Zhang, Liu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303224/ https://www.ncbi.nlm.nih.gov/pubmed/28187731 http://dx.doi.org/10.1186/s12891-017-1399-2

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