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Leveraging genome-wide datasets to quantify the functional role of the anti-Shine–Dalgarno sequence in regulating translation efficiency
Studies dating back to the 1970s established that sequence complementarity between the anti-Shine–Dalgarno (aSD) sequence on prokaryotic ribosomes and the 5′ untranslated region of mRNAs helps to facilitate translation initiation. The optimal location of aSD sequence binding relative to the start co...
Autores principales: | Hockenberry, Adam J., Pah, Adam R., Jewett, Michael C., Amaral, Luís A. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303271/ https://www.ncbi.nlm.nih.gov/pubmed/28100663 http://dx.doi.org/10.1098/rsob.160239 |
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