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Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901

BACKGROUND: Dispersal of glioblastoma (GBM) cells leads to recurrence and poor prognosis. Accordingly, molecular pathways involved in dispersal are potential therapeutic targets. The mitogen activated protein kinase/extracellular signal regulated kinase (MAPK/ERK) pathway is commonly dysregulated in...

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Detalles Bibliográficos
Autores principales:	Shannon, Stephen, Jia, Dongxuan, Entersz, Ildiko, Beelen, Paul, Yu, Miao, Carcione, Christian, Carcione, Jonathan, Mahtabfar, Aria, Vaca, Connan, Weaver, Michael, Shreiber, David, Zahn, Jeffrey D., Liu, Liping, Lin, Hao, Foty, Ramsey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303286/ https://www.ncbi.nlm.nih.gov/pubmed/28187762 http://dx.doi.org/10.1186/s12885-017-3107-x

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