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Incorporating prior biological knowledge for network-based differential gene expression analysis using differentially weighted graphical LASSO

BACKGROUND: Conventional differential gene expression analysis by methods such as student’s t-test, SAM, and Empirical Bayes often searches for statistically significant genes without considering the interactions among them. Network-based approaches provide a natural way to study these interactions...

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Detalles Bibliográficos
Autores principales:	Zuo, Yiming, Cui, Yi, Yu, Guoqiang, Li, Ruijiang, Ressom, Habtom W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303311/ https://www.ncbi.nlm.nih.gov/pubmed/28187708 http://dx.doi.org/10.1186/s12859-017-1515-1

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