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Repercussions of intraalveolar placement of combination of 0.2% chlorhexidine & 10 Mg metronidazole gel on the occurrence of dry sockets- A randomized control trial

BACKGROUND: To evaluate the effects of intraalveolar placement of gel containing 0.2% chlorhexidine and 10gm of metronidazole on the incidence of alveolar osteitis. MATERIAL AND METHODS: A total of 300 impacted third molars were extracted in 150 patients enrolled in this trial. In each subject a soc...

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Autores principales: Kaur, Jasleen, Raval, Rushik, Bansal, Anupam, Kumawat, Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303332/
https://www.ncbi.nlm.nih.gov/pubmed/28210450
http://dx.doi.org/10.4317/jced.53262
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author Kaur, Jasleen
Raval, Rushik
Bansal, Anupam
Kumawat, Vinod
author_facet Kaur, Jasleen
Raval, Rushik
Bansal, Anupam
Kumawat, Vinod
author_sort Kaur, Jasleen
collection PubMed
description BACKGROUND: To evaluate the effects of intraalveolar placement of gel containing 0.2% chlorhexidine and 10gm of metronidazole on the incidence of alveolar osteitis. MATERIAL AND METHODS: A total of 300 impacted third molars were extracted in 150 patients enrolled in this trial. In each subject a socket was randomly selected and packed to the crest of alveolar ridge with the gel. The contralateral socket was packed with placebo dressing. The occurrence of dry socket was assessed during 3rd and 5th postoperative days .The data was analysed using a meta analytical program. STUDY DESIGN: Double blind, prospective, placebo controlled trial. RESULTS: The combination of metronidazole + chlorhexidine gel significantly reduced dry socket incidence from 22.6% to 6.6% (P ≤ 0.001) [McNemar and chi-square tests]. CONCLUSIONS: The decrease in incidence of adverse reactions and complications related to local application of metronidazole and chlorhexidine gel explains its clinical use, specifically in mandibular molar extractions where the chances of dry sockets are high. Key words:Chlorhexidine, dry socket, intra-alveolar, metronidazole, placebo.
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spelling pubmed-53033322017-02-16 Repercussions of intraalveolar placement of combination of 0.2% chlorhexidine & 10 Mg metronidazole gel on the occurrence of dry sockets- A randomized control trial Kaur, Jasleen Raval, Rushik Bansal, Anupam Kumawat, Vinod J Clin Exp Dent Research BACKGROUND: To evaluate the effects of intraalveolar placement of gel containing 0.2% chlorhexidine and 10gm of metronidazole on the incidence of alveolar osteitis. MATERIAL AND METHODS: A total of 300 impacted third molars were extracted in 150 patients enrolled in this trial. In each subject a socket was randomly selected and packed to the crest of alveolar ridge with the gel. The contralateral socket was packed with placebo dressing. The occurrence of dry socket was assessed during 3rd and 5th postoperative days .The data was analysed using a meta analytical program. STUDY DESIGN: Double blind, prospective, placebo controlled trial. RESULTS: The combination of metronidazole + chlorhexidine gel significantly reduced dry socket incidence from 22.6% to 6.6% (P ≤ 0.001) [McNemar and chi-square tests]. CONCLUSIONS: The decrease in incidence of adverse reactions and complications related to local application of metronidazole and chlorhexidine gel explains its clinical use, specifically in mandibular molar extractions where the chances of dry sockets are high. Key words:Chlorhexidine, dry socket, intra-alveolar, metronidazole, placebo. Medicina Oral S.L. 2017-02-01 /pmc/articles/PMC5303332/ /pubmed/28210450 http://dx.doi.org/10.4317/jced.53262 Text en Copyright: © 2017 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Kaur, Jasleen
Raval, Rushik
Bansal, Anupam
Kumawat, Vinod
Repercussions of intraalveolar placement of combination of 0.2% chlorhexidine & 10 Mg metronidazole gel on the occurrence of dry sockets- A randomized control trial
title Repercussions of intraalveolar placement of combination of 0.2% chlorhexidine & 10 Mg metronidazole gel on the occurrence of dry sockets- A randomized control trial
title_full Repercussions of intraalveolar placement of combination of 0.2% chlorhexidine & 10 Mg metronidazole gel on the occurrence of dry sockets- A randomized control trial
title_fullStr Repercussions of intraalveolar placement of combination of 0.2% chlorhexidine & 10 Mg metronidazole gel on the occurrence of dry sockets- A randomized control trial
title_full_unstemmed Repercussions of intraalveolar placement of combination of 0.2% chlorhexidine & 10 Mg metronidazole gel on the occurrence of dry sockets- A randomized control trial
title_short Repercussions of intraalveolar placement of combination of 0.2% chlorhexidine & 10 Mg metronidazole gel on the occurrence of dry sockets- A randomized control trial
title_sort repercussions of intraalveolar placement of combination of 0.2% chlorhexidine & 10 mg metronidazole gel on the occurrence of dry sockets- a randomized control trial
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303332/
https://www.ncbi.nlm.nih.gov/pubmed/28210450
http://dx.doi.org/10.4317/jced.53262
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