Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event?

Leflunomide is a member of the disease modifying anti-rheumatic drugs group used as a treatment modality in active rheumatoid and psoriatic arthritis. “Oral ulcers” are reported in 3-5% of leflunomide medicated rheumatoid arthritis patients with adverse events, but they are not described in detail i...

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Autores principales: Kalogirou, Eleni-Marina, Katsoulas, Nikolaos, Tosios, Konstantinos I., Lazaris, Andreas C., Sklavounou, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303339/
https://www.ncbi.nlm.nih.gov/pubmed/28210457
http://dx.doi.org/10.4317/jced.53428
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author Kalogirou, Eleni-Marina
Katsoulas, Nikolaos
Tosios, Konstantinos I.
Lazaris, Andreas C.
Sklavounou, Alexandra
author_facet Kalogirou, Eleni-Marina
Katsoulas, Nikolaos
Tosios, Konstantinos I.
Lazaris, Andreas C.
Sklavounou, Alexandra
author_sort Kalogirou, Eleni-Marina
collection PubMed
description Leflunomide is a member of the disease modifying anti-rheumatic drugs group used as a treatment modality in active rheumatoid and psoriatic arthritis. “Oral ulcers” are reported in 3-5% of leflunomide medicated rheumatoid arthritis patients with adverse events, but they are not described in detail in the literature. We present a case of an ulcer in the tongue of a rheumatoid arthritis patient managed with leflunomide and contemplate on its pathogenesis. Key words:Leflunomide, oral ulcer, DHODH.
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spelling pubmed-53033392017-02-16 Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event? Kalogirou, Eleni-Marina Katsoulas, Nikolaos Tosios, Konstantinos I. Lazaris, Andreas C. Sklavounou, Alexandra J Clin Exp Dent Case Report Leflunomide is a member of the disease modifying anti-rheumatic drugs group used as a treatment modality in active rheumatoid and psoriatic arthritis. “Oral ulcers” are reported in 3-5% of leflunomide medicated rheumatoid arthritis patients with adverse events, but they are not described in detail in the literature. We present a case of an ulcer in the tongue of a rheumatoid arthritis patient managed with leflunomide and contemplate on its pathogenesis. Key words:Leflunomide, oral ulcer, DHODH. Medicina Oral S.L. 2017-02-01 /pmc/articles/PMC5303339/ /pubmed/28210457 http://dx.doi.org/10.4317/jced.53428 Text en Copyright: © 2017 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kalogirou, Eleni-Marina
Katsoulas, Nikolaos
Tosios, Konstantinos I.
Lazaris, Andreas C.
Sklavounou, Alexandra
Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event?
title Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event?
title_full Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event?
title_fullStr Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event?
title_full_unstemmed Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event?
title_short Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event?
title_sort non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. an adverse drug event?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303339/
https://www.ncbi.nlm.nih.gov/pubmed/28210457
http://dx.doi.org/10.4317/jced.53428
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