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Icariin Inhibits AMPK-Dependent Autophagy and Adipogenesis in Adipocytes In vitro and in a Model of Graves' Orbitopathy In vivo

Graves' orbitopathy (GO), an extrathyroidal manifestation of Graves' disease, is an inflammatory autoimmune disorder of the orbit that involves the differentiation of precursor cells into mature adipocytes and retro-orbital adipose tissue accumulation. Here, we examined the involvement of...

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Detalles Bibliográficos
Autores principales: Li, Hong, Yuan, Yifei, Zhang, Yali, Zhang, Xia, Gao, Long, Xu, Rongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303717/
https://www.ncbi.nlm.nih.gov/pubmed/28243204
http://dx.doi.org/10.3389/fphys.2017.00045