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The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD

Expansion of a hexanucleotide (GGGGCC) repeat in the gene chromosome 9 open reading frame 72 (C9ORF72) is the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia (FTD). Three non-exclusive mechanisms have been proposed to contribute to the pathology initiated by this genet...

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Detalles Bibliográficos
Autores principales:	Freibaum, Brian D., Taylor, J. Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303742/ https://www.ncbi.nlm.nih.gov/pubmed/28243191 http://dx.doi.org/10.3389/fnmol.2017.00035

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