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Functionality and opposite roles of two interleukin 4 haplotypes in immune cells

Cytokines expression can be influenced by polymorphisms in their respective coding genes. We associated the CTI/TTD haplotype (Hap-1) and TCI/CCI haplotype (Hap-2) in the IL4 gene formed by the −590, +33 and variable number of tandem repeat polymorphisms with the severity of chronic periodontitis in...

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Detalles Bibliográficos
Autores principales: Anovazzi, G, Medeiros, M C, Pigossi, S C, Finoti, L S, Souza Moreira, T M, Mayer, M P A, Zanelli, C F, Valentini, S R, Rossa-Junior, C, Scarel-Caminaga, R M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303765/
https://www.ncbi.nlm.nih.gov/pubmed/28053321
http://dx.doi.org/10.1038/gene.2016.47

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