DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis

Novel therapeutics are required for improving the management of chronic inflammatory diseases. Aptamers are single-stranded RNA or DNA molecules that have recently shown utility in a clinical setting, as they can specifically neutralize biomedically relevant proteins, particularly cell surface and e...

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Detalles Bibliográficos
Autores principales: Mor-Vaknin, Nirit, Saha, Anjan, Legendre, Maureen, Carmona-Rivera, Carmelo, Amin, M Asif, Rabquer, Bradley J., Gonzales-Hernandez, Marta J., Jorns, Julie, Mohan, Smriti, Yalavarthi, Srilakshmi, Pai, Dave A., Angevine, Kristine, Almburg, Shelley J., Knight, Jason S., Adams, Barbara S., Koch, Alisa E., Fox, David A., Engelke, David R., Kaplan, Mariana J., Markovitz, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303823/
https://www.ncbi.nlm.nih.gov/pubmed/28165452
http://dx.doi.org/10.1038/ncomms14252

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