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Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis

Subglottic Eosinophilic Angiocentric Fibrosis (EAF) is an extremely rare disease of an elusive aetiology. It is chronically progressive benign condition that causes narrowing of the subglottic region leading to dysphonia and airway compromise. The diagnosis is historical and imaging is nonspecific....

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Autores principales: Keogh, Ivan, O'Connell, Rohana, Hynes, Sean, Lang, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303848/
https://www.ncbi.nlm.nih.gov/pubmed/28251006
http://dx.doi.org/10.1155/2017/2381786
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author Keogh, Ivan
O'Connell, Rohana
Hynes, Sean
Lang, John
author_facet Keogh, Ivan
O'Connell, Rohana
Hynes, Sean
Lang, John
author_sort Keogh, Ivan
collection PubMed
description Subglottic Eosinophilic Angiocentric Fibrosis (EAF) is an extremely rare disease of an elusive aetiology. It is chronically progressive benign condition that causes narrowing of the subglottic region leading to dysphonia and airway compromise. The diagnosis is historical and imaging is nonspecific. We report a case xc of 56-year-old lady referred to our institution with globus sensation, hoarseness, and mild stridor. Incidental subglottic mass was found at time of diagnostic microlaryngoscopy and biopsy confirmed subglottic EAF. All laboratory investigations were unremarkable. Lesion was removed with laryngeal microdebrider and three courses of intravenous dexamethasone were administered. Patient's postoperative period was uneventful and had remained disease free for 1 year. To date, no consensus has been reached on the optimal treatment of subglottic EAF. We recommend regular follow-up to detect early recurrence.
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spelling pubmed-53038482017-03-01 Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis Keogh, Ivan O'Connell, Rohana Hynes, Sean Lang, John Case Rep Otolaryngol Case Report Subglottic Eosinophilic Angiocentric Fibrosis (EAF) is an extremely rare disease of an elusive aetiology. It is chronically progressive benign condition that causes narrowing of the subglottic region leading to dysphonia and airway compromise. The diagnosis is historical and imaging is nonspecific. We report a case xc of 56-year-old lady referred to our institution with globus sensation, hoarseness, and mild stridor. Incidental subglottic mass was found at time of diagnostic microlaryngoscopy and biopsy confirmed subglottic EAF. All laboratory investigations were unremarkable. Lesion was removed with laryngeal microdebrider and three courses of intravenous dexamethasone were administered. Patient's postoperative period was uneventful and had remained disease free for 1 year. To date, no consensus has been reached on the optimal treatment of subglottic EAF. We recommend regular follow-up to detect early recurrence. Hindawi Publishing Corporation 2017 2017-01-30 /pmc/articles/PMC5303848/ /pubmed/28251006 http://dx.doi.org/10.1155/2017/2381786 Text en Copyright © 2017 Ivan Keogh et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Keogh, Ivan
O'Connell, Rohana
Hynes, Sean
Lang, John
Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_full Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_fullStr Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_full_unstemmed Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_short Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_sort eosinophilic angiocentric fibrosis as a stenosing lesion in the subglottis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303848/
https://www.ncbi.nlm.nih.gov/pubmed/28251006
http://dx.doi.org/10.1155/2017/2381786
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