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Preferential Lineage-Specific Differentiation of Osteoblast-Derived Induced Pluripotent Stem Cells into Osteoprogenitors

While induced pluripotent stem cells (iPSCs) hold great clinical promise, one hurdle that remains is the existence of a parental germ-layer memory in reprogrammed cells leading to preferential differentiation fates. While it is problematic for generating cells vastly different from the reprogrammed...

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Detalles Bibliográficos
Autores principales:	Roberts, Casey L., Chen, Silvia S., Murchison, Angela C., Ogle, Rebecca A., Francis, Michael P., Ogle, Roy C., Sachs, Patrick C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303871/ https://www.ncbi.nlm.nih.gov/pubmed/28250775 http://dx.doi.org/10.1155/2017/1513281

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