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DDX53 Promotes Cancer Stem Cell-Like Properties and Autophagy

Although cancer/testis antigen DDX53 confers anti-cancer drug-resistance, the effect of DDX53 on cancer stem cell-like properties and autophagy remains unknown. MDA-MB-231 (CD133(+)) cells showed higher expression of DDX53, SOX-2, NANOG and MDR1 than MDA-MB-231 (CD133(−)). DDX53 increased in vitro s...

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Detalles Bibliográficos
Autores principales: Kim, Hyuna, Kim, Youngmi, Jeoung, Dooil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303889/
https://www.ncbi.nlm.nih.gov/pubmed/28152297
http://dx.doi.org/10.14348/molcells.2017.2258