High Kynurenine (a Tryptophan Metabolite) Predicts Remission in Patients with Major Depression to Add-on Treatment with Celecoxib

BACKGROUND: Signs of an inflammatory process have been described in major depression. METHODS: In a double-blind, randomized study of celecoxib or placebo add-on to reboxetine in 40 depressed patients, celecoxib treatment has beneficial effects. In order to evaluate the tryptophan/kynurenine metabol...

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Detalles Bibliográficos
Autores principales: Krause, Daniela, Myint, Aye-Mu, Schuett, Christine, Musil, Richard, Dehning, Sandra, Cerovecki, Anja, Riedel, Michael, Arolt, Volker, Schwarz, Markus J., Müller, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304105/
https://www.ncbi.nlm.nih.gov/pubmed/28243208
http://dx.doi.org/10.3389/fpsyt.2017.00016

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