Applying phasor approach analysis of multiphoton FLIM measurements to probe the metabolic activity of three-dimensional in vitro cell culture models

Fluorescence lifetime imaging microscopy (FLIM) can measure and discriminate endogenous fluorophores present in biological samples. This study seeks to identify FLIM as a suitable method to non-invasively detect a shift in cellular metabolic activity towards glycolysis or oxidative phosphorylation i...

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Detalles Bibliográficos
Autores principales: Lakner, Pirmin H., Monaghan, Michael G., Möller, Yvonne, Olayioye, Monilola A., Schenke-Layland, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304149/
https://www.ncbi.nlm.nih.gov/pubmed/28211922
http://dx.doi.org/10.1038/srep42730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304149/
https://www.ncbi.nlm.nih.gov/pubmed/28211922
http://dx.doi.org/10.1038/srep42730

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