Cargando…
Inhibitory effects of cholinesterase inhibitor donepezil on the Kv1.5 potassium channel
Kv1.5 channels carry ultra-rapid delayed rectifier K(+) currents in excitable cells, including neurons and cardiac myocytes. In the current study, the effects of cholinesterase inhibitor donepezil on cloned Kv1.5 channels expressed in HEK29 cells were explored using whole-cell recording technique. E...
Autores principales: | Li, Kai, Cheng, Neng, Li, Xian-Tao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304190/ https://www.ncbi.nlm.nih.gov/pubmed/28198801 http://dx.doi.org/10.1038/srep41509 |
Ejemplares similares
-
The Inhibitory Effects of Ca(2+) Channel Blocker Nifedipine on Rat Kv2.1 Potassium Channels
por: Li, Xian-Tao, et al.
Publicado: (2015) -
Multifunctional Donepezil Analogues as Cholinesterase and BACE1 Inhibitors
por: Green, Keith D., et al.
Publicado: (2018) -
Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors
por: Zhao, Lingyue, et al.
Publicado: (2022) -
The antidiabetic drug rosiglitazone blocks Kv1.5 potassium channels in an open state
por: Lee, Hyang Mi, et al.
Publicado: (2022) -
Challenges Faced with Small Molecular Modulators of Potassium Current Channel Isoform Kv1.5
por: Zhao, Zefeng, et al.
Publicado: (2019)