Crucial Role of Mesangial Cell-derived Connective Tissue Growth Factor in a Mouse Model of Anti-Glomerular Basement Membrane Glomerulonephritis

Connective tissue growth factor (CTGF) coordinates the signaling of growth factors and promotes fibrosis. Neonatal death of systemic CTGF knockout (KO) mice has hampered analysis of CTGF in adult renal diseases. We established 3 types of CTGF conditional KO (cKO) mice to investigate a role and sourc...

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Detalles Bibliográficos
Autores principales: Toda, Naohiro, Mori, Kiyoshi, Kasahara, Masato, Ishii, Akira, Koga, Kenichi, Ohno, Shoko, Mori, Keita P., Kato, Yukiko, Osaki, Keisuke, Kuwabara, Takashige, Kojima, Katsutoshi, Taura, Daisuke, Sone, Masakatsu, Matsusaka, Taiji, Nakao, Kazuwa, Mukoyama, Masashi, Yanagita, Motoko, Yokoi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304211/
https://www.ncbi.nlm.nih.gov/pubmed/28191821
http://dx.doi.org/10.1038/srep42114

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